Cisapride
Adverse Effect: Loss of cisapride efficacy Clinical Management: The beneficial effects of cisapride are expected to be largely lost if an anticholinergic medication such as clidinium is given concomitantly.
Procainamide
Adverse Effect: additive antivagal effects on A-V nodal conduction Clinical Management: Monitor heart rate and ECG in patients given procainamide concomitantly with an anticholinergic medication. |